Axsome Therapeutics, Inc. (AXSM) — Insider Trading

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This analysis covers the filing from 2026-04-23. New 10-K, 10-Q and 8-K filings are analyzed the moment they are released — exclusively in the app.

Earlier Insider Trading filings

Filed: 2026-04-23
  • CEO Herriot Tabuteau acquired 24,081 Performance Stock Units (PSUs) on 04/21/2026, representing contingent rights to common stock that vest upon achievement of sales and commercial launch milestones.
  • The PSU grant demonstrates management's confidence in Axsome's commercial prospects and ability to hit revenue targets, as vesting is tied to specific sales milestones rather than time-based vesting.
  • As both Director, 10% Owner, and CEO, Tabuteau's significant equity stake aligns his personal interests with shareholder value creation and successful product commercialization.
Filed: 2026-04-23
  • Chief Commercial Officer Ari Maizel exercised 7,500 stock options at $70.73 per share and immediately sold all 7,500 shares at an average price of $182.42, realizing a substantial gain of approximately $835,175 or 157% profit within the same day.
  • The transaction was executed under a pre-approved Rule 10b5-1 trading plan, indicating this was a planned, systematic transaction rather than a reactive market decision, which reduces concerns about negative insider sentiment.
  • After the sale, Maizel retains 23,710 shares of direct beneficial ownership, demonstrating continued meaningful equity stake in the company despite the full liquidation of this particular option exercise.
  • The significant gap between the exercise price ($70.73) and sale price ($182.42) suggests substantial stock appreciation since the options were granted, reflecting positive company performance or market conditions.
Filed: 2026-04-23
  • Chief Commercial Officer Ari Maizel received 7,224 Performance Stock Units (PSUs) on 04/21/2026, contingent upon achievement of sales and commercial launch milestones, indicating confidence in upcoming product commercialization targets.
  • The PSU grant is tied to specific performance metrics rather than automatic vesting, suggesting management's compensation is directly aligned with company's commercial execution and revenue generation goals.
  • This executive compensation structure demonstrates the company's focus on near-term commercialization success, particularly relevant given Maizel's role as Chief Commercial Officer overseeing market launch and sales efforts.
Filed: 2026-04-23
  • CFO Nick Pizzie acquired 8,188 performance stock units (PSUs) on 04/21/2026, representing contingent rights to common shares with $0 exercise price, indicating a compensation award rather than open market purchase.
  • PSU vesting is contingent upon achievement of sales and commercial launch milestones combined with continued service, suggesting management's compensation is directly tied to commercialization success of company products.
  • The grant of PSUs to the CFO signals confidence in upcoming revenue-generating milestones and product launches, though the contingent nature means these shares have not yet been earned.
Filed: 2026-04-23
  • Hunter Murdock, General Counsel of Axsome Therapeutics, acquired 7,224 performance stock units (PSUs) on April 21, 2026, representing a contingent right to receive common shares upon achievement of sales and commercial launch milestones.
  • The PSU grant is contingent on specific business milestones rather than time-based vesting, indicating management confidence in upcoming product commercialization or sales targets for the company's pipeline.
  • As General Counsel and an officer, Murdock's acceptance of milestone-based equity compensation suggests alignment with company growth objectives, though the zero upfront value indicates these are future-conditional awards rather than immediate wealth transfers.
Filed: 2026-02-10
  • The reporting person, Mark Coleman, exercised 5,193 stock options at $8.02 per share, indicating an increase in his direct ownership of Axsome Therapeutics' common stock.
  • Coleman also holds 403,856 shares indirectly through an entity over which he has voting and dispositive power, suggesting he maintains a significant ownership stake in the company.
  • The exercise of options and holding of the underlying shares signals the reporting person's confidence in Axsome Therapeutics' long-term prospects.
Filed: 2026-01-23
  • The reporting person, Nick Pizzie, who is the Chief Financial Officer of Axsome Therapeutics, Inc., exercised 12,000 stock options and immediately sold the underlying shares for a total transaction value of around $2.25 million.
  • The transaction was executed pursuant to a pre-approved 10b5-1 trading plan, indicating pre-planned portfolio management rather than a one-off transaction.
  • The reporting person continues to hold a direct ownership stake of 42,588 shares in the company, in addition to an indirect ownership of 488 shares held in custodial accounts for his children.
Filed: 2026-01-23
  • Ari Maizel, the Chief Commercial Officer of Axsome Therapeutics, Inc., exercised 7,500 stock options and subsequently sold the same number of shares on January 21, 2026.
  • The stock option exercise price was $70.73 per share, while the sale price was a weighted average of $184.44 per share, suggesting a significant gain for the reporting person.
  • This transaction was conducted pursuant to a pre-approved 10b5-1 plan, indicating a planned and structured approach to the insider's trading activity.
Filed: 2026-01-07
  • Axsome Therapeutics' CEO Herriot Tabuteau exercised and sold a significant number of stock options in early January 2026, indicating insider selling activity.
  • The sales were executed pursuant to a pre-approved 10b5-1 trading plan, suggesting a planned and systematic liquidation of Tabuteau's equity holdings.
  • Tabuteau also holds a large indirect beneficial ownership stake in Axsome, suggesting he maintains a substantial economic interest in the company.

Other reports for Axsome Therapeutics, Inc.

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